A US aircraft killed 15 worshipers in an airstrike on a mosque in al-Haditha city in Western Al-Anbar province on Wednesday.
The airstrike was launched as 1,400 US military troops deployed at Ain Al-Assad military base in the same province.
Since August, the US and some of its allies have been conducting airstrikes against what they say are the ISIL positions in Iraq. Some members of the US-led coalition against ISIL also started a similar bombing campaign inside Syria in September.
However, the raids have so far failed to dislodge the Takfiri group who has occupied swathes of land in Iraq and Syria.
The US airstrikes have led to the killing of many civilians both in Iraq and Syria.
Over 65 civilians were killed during massive airstrikes of the US-led coalition in Anbar province in early October.
A military source told National Iraqi news agency that the US-led air strikes on the positions of the ISIL in the city of Ramadi, left 65 civilians dead, including women and children, without inflicting any casualty on the Takfiri terrorist group.
Two weeks later in the same month, tens of Iraqi popular forces, fighting the terrorist groups, were killed in the US airstrikes against their positions around Mahmoudiya city, South of Baghdad.
“The US attacks targeted the volunteer forces around Mahmoudiya which led to the complete destruction of a battalion and martyrdom of tens of people,” an Iraqi security force told FNA in mid October.
The source said given the US blind attacks on popular forces, the residents of Mahmoudiya were due to hold protest rallies to call on the religious leaders, the parliament and the government to adopt a serious stance against the massacre of the people by the so-called anti-ISIL coalition.
A few days earlier, US-led forces killed ten civilians in two airstrikes in Syria, according to a Syrian opposition monitoring group.
The Syrian Observatory for Human Rights said seven civilians were killed when an airstrike hit a gas plant near the town of al-Khasham is the Eastern Deir Ezzur province, and three civilians were killed in an airstrike a day earlier in the Northeastern province of al-Hassakah.
The coalition has been bombing ISIL targets in Iraq since August and extended the campaign to Syria in September.
Also, a US airstrike killed at least 50 Syrian civilians late in December when it reportedly targeted a headquarters of the ISIL in Northern Syria. According to a report provided by an eyewitness, the civilians were killed in the town of al-Bab, close to the Turkish border, when the US aircraft struck on the evening of December 28.